Antimicrobial Mattress Covers & Protectors

This mattress protector guards your bed against everyday spills, allergens, and unwanted pests. Made from soft cotton terry cloth, it offers a breathable barrier that keeps your mattress fresh while maintaining a comfortable sleeping surface. The fitted design fits snugly over the top and sides of your mattress to stay securely in place night after night. It’s easy to maintain and machine washable, making cleanup a simple part of your laundry routine. Plus, it helps extend the life of your mattress by shielding it from moisture and wear.

This Terry cloth mattress cover is so comfortable, it made me feel like I was floating on a cloud. Looks and feels clean and fresh.. Frances. Thornton, CO. Sat, 17 Oct 2026

This standard mattress protector creates a clean, hypoallergenic barrier for a great night's sleep. Its ultra-tech polyester blend, derived from rayon from bamboo, keeps your sleep surface feeling cool throughout the night. This piece guards against spills and moisture, actively extending the life of your mattress. It is also antimicrobial, odor resistant, and resists mold and mildew for a fresh feel. It is offered in several sizes to fit your bed. Plus, this fitted protector secures easily and provides coverage for even deep mattresses.

I’m very happy with this fitted sheet. The material feels soft, smooth, and comfortable to the touch, and the overall quality is excellent. The fabric feels well-made and durable, with a nice texture that gives it a premium feel. It fits my mattress nicely and stays securely in place without slipping or bunching up. The stitching and finishing are neat, and the overall craftsmanship is impressive. It’s comfortable to sleep on and looks great on the bed. Overall, I’m very satisfied with this purchase. It offers a great combination of comfort, quality, and practicality. I would definitely recommend it!. Nat. New York. Mon, 09 Nov 2026

Sleep soundly, worry-free with our Breathable Cotton Waterproof Mattress Protector! Made from 100% natural cotton, this soft & cooling protector provides a barrier against accidents and spills while still allowing for airflow and breathability. The waterproof coating ensures a dry and comfortable sleeping surface, while the cotton fabric keeps you cozy and snug. Perfect for families with young children, pets, or those who tend to sleep hot, this protector is easy to wash and dry, ensuring a fresh start every morning. Upgrade your bedding routine with our eco-friendly, 100% cotton waterproof mattress protector - your body (and the planet) will thank you

Great item and excellent services. I enjoy the esthetic value this product added to my home and my guests will always ask where I got them and I’ll simply say “Wayfair is the way to go”.. Anonymous. Sat, 10 Oct 2026

BEDLORE® dedicates the best sleep experience to every customer. The BEDLORE® Mattress protector features a unique classic coin quilt pattern and is crafted from brushed microfiber, which provides a soft and comfortable sleeping experience. The premium waterproof design protects your mattress from potential damage and stains caused by liquid spills and accidents. The deep pocket design ensures a secure fit for mattresses with a maximum depth of 18 inches, so you will no longer feel the sheets slipping or sliding, and this mattress protector can withstand regular washing and maintain its quality and function over time.

Fits perfect and looks good, I would buy again.. Ivy. Williamsville, NY. Fri, 16 Oct 2026

Chill out and stay cool, comfy, and safe with the power chill antimicrobial cooling mattress protector.

Thinner than I thought . But it’s water proof and that’s why I bought it.. Maria. Monroe, CT. Thu, 12 Nov 2026

This fitted mattress protector gives you peace of mind while keeping your bed fresh and clean. Crafted from polyester, it creates a protective barrier that stands up to spills and splashes. We love that the breathable fabric promotes airflow to help you stay cool throughout the night. It easily slides over your mattress for a secure fit that stays in place even as you move. This essential layer provides a shield against common allergens like dust mites and bed bugs to support a restful environment. It also resists wrinkles and stains for effortless everyday maintenance.

Lightweight and soft and no krinkling waterproof mattress cover! Happy with this purchase.. Steph. Mon, 21 Sep 2026

Purecare's Cooling Mattress Protector combines a specially designed lightweight OmniGuard® Advance performance fabric with rapid chill cooling FRÍO® fibers for a cleaner, cooler sleep surface. The cooling fibers disperse body heat through the surface of the protector at a rate five times faster than that of regular polyester, tunneling heat away from the body as you sleep. FRÍO rapid chill cooling fibers are built into the fabric, so the cooling effects of this material will not wash out, lasting the lifetime of the protector. Purecare's clinically proven 5-Sided mattress covers fit like a fitted sheet around your mattress. Our covers utilize double-bound MiteTight® seams, combined with our OmniGuard Advance fabric, which provides quiet, cool, breathable protection. Great for allergy sufferers, our protectors provide a physical barrier against allergens, dust mites, stains, moisture, mold, and mildew. Our PureCare 5-Sided protector works with any mattress type, including memory foam, innerspring, gel, or latex mattresses. Completely washable, our 5-Sided protectors are specially designed so that you can wash and dry on hot settings for optimal comfort. Mattress covers conform to strict class one medically recommended allergen standards. All Purecare Mattress Protectors are treated with antimicrobial silver product protection treatment that inhibits bacteria, mold, and mildew that causes deterioration, stains, and odors on this product.

Got is on sale, it does feel pretty cool to the touch. The only complaint but really it’s not that bad is it has a bit of a chemical smell coming out of the box. Other than that, it’s awesome.. Anonymous. Thu, 27 Aug 2026

This mattress protector will keep your mattress clean, dry from spills or accidents and look fresh and new. This mattress protector has a patented method, GhostGrip, so it will stay on your mattress properly and never pops off.

Good protection for my mattress.. Cynthia. Owatonna, MN. Tue, 20 Apr 2021

Crafted with Dri-Tec moisture-wicking technology, the Bedgear Moisture-Wicking Mattress Cover ensures a restful night's sleep. Designed in a lofted honeycomb pattern, this mattress protector has soft, breathable layers that enhance airflow for maximum nighttime comfort. It also keeps your mattress free from spills and is easy to care for as it is machine washable and dryer-friendly.

Amazing. I will definitely buy again.. Elizabeth. US. Mon, 07 Sep 2026

Form a soft, sealed barrier around your mattress with this waterproof and hypoallergenic mattress protector. The secure fit of this cover stretches to fit any mattress up to 22 inches thick (8 inches thick for any baby mattress), and its fitted construction makes it easy to remove for washing. The hypoallergenic cotton terry platform provides a comfortable sleeping surface while the sturdy microfiber base forms a waterproof barrier to protect your mattress against unwanted stains, spills, and moisture. Available in an assortment of sizes to fit every bed in your home.

prefect for the guest room, never have to worry with guests staying over now. Timothy. US. Mon, 14 Sep 2026

The bamboo fabric is noiseless, breathable & provides cooling comfort. Our hypoallergenic mattress cover is ideal for people who are suffering from allergies, asthma, or eczema since it will effectively seal your mattress and keeps dust mites and other allergens away from your bed.16-Inch-deep pocket, which is suitable for all types of bed& also completely noise-free and does not produce any crinkling sound when slept on. Ultra-Strong and Soft Bamboo Polyester Blend (70% Rayon Derived from bamboo/ 30% Polyester). The cooling mattress protectors are also free from PVC, Phthalate, and vinyl. Oeko-TexStandard 100 factory certification ensures that the fabric meets the safety and environmental standards. Great for people with kids, pets, etc.

I have been sleeping on this mattress for 2 years now. It’s still in excellent condition and I sleep well every night.. Anonymous. Fri, 17 Jul 2026

Waterproof Mattress Protector: Our mattress protectors are completely waterproof and breathable allowing for air circulation and they effectively repel all liquids including accidental spills and bodily fluids such as sweat or urine. They were engineered to endure the endless rigor of multiple spills, soils, and washes.

The elastics are really stretched to their limit. They turn over under our king-size mattress. Otherwise pleased with comfort on our bed.. Linda. Calgary, AB. Fri, 13 Nov 2026

Designed for maximum breathability, the Air-X performance mattress protector guards against spills while keeping you comfortable with two air cushion layers that allow airflow all night long, helping your body naturally regulate its ideal sleep temperature. This protector features a powerband for secure fit and grip, keeping this layer smooth and invisible beneath your sheets – perfect for adjustable bases.

Wonderful mattress protector! This product is well made very thick, and fits plush mattresses. The product has grey top which is breathable technology keeping it cool. I’m really pleased with this product and would recommend to others in need a quality mattress protector.. Crystal. California. Tue, 06 Dec 2022

It’s no use crying over spilled milk and you will never have to again with this Premium Hypoallergenic Waterproof. You can keep your mattress looking and feeling brand new by protecting it against dust, spills, and even normal wears and tears. Rest assured a good night’s sleep not worrying about dirt, dust mites, or allergens. Breathable, noiseless, and waterproof with the combination of the soft terry face fabric combined with the TPU (Thermoplastic Polyurethane) reverse fabric allowing air circulation through your mattress, while repelling fluids away from it. This mattress protector will fit snug onto your mattress with elastic bands around it, which also allows it to be easily removable and machine washable.

Very good. Jose. New Brunswick, NJ. Mon, 24 Aug 2026

This Encasement Mattress Protector surrounds your mattress, protecting the top, bottom and sides from fluids, stains, dust mites, and allergens, and helps keep bed bugs from reaching your mattress. Made of lightweight polyester jersey fabric with a breathable polyurethane backing, it offers complete protection while maintaining the feel of your mattress. This protector is designed to provide reliable protection without noise or excessive heat. It zips closed for a smooth, even fit. For convenience and a healthy sleep environment, the encasement is machine washable and dryer safe.

Great quality! Durable and soft material. Jenny. Bronx, NY. Sat, 25 Apr 2026

The mattress cover is the perfect protector to keep your mattress clean and in great shape! Our high-end, luxurious mattress covers are completely waterproof and will protect against spills, stains, allergies, bed-wetting, dust mites, bed bugs, and mold. Our double brushed fabric is designed to be tough but breathable to keep you cool as well as protect your mattress. The extra strong elastic will hug your mattress and fit mattresses with pockets as deep as 18 inches. These covers can be washed and dried on low heat.

Use this lab-tested matteress encasement to keep your mattress and bed clean, healthy, and comfortable

I like that it zips. Mine did have a little tear at the seam, right out of the package, But Wayfair made that right.. Deena. Hamilton, OH. Sat, 17 Oct 2026

Featuring flex-and-fit motion-activated technology, BEDGEAR’s StretchWick fabric construction complements the contours of the mattress and body while providing all-way stretch for a flexible fit. With a breathable waterproof barrier to protect your mattress, all-way stretch provides resistance-free comfort with enhanced airflow. The flex-and-fit motion-activated technology allows all-way stretch to provide resistance-free comfort while you sleep and a flexible fit on your mattress, even when using an adjustable base. StretchWick has a lightweight and moisture-wicking fabric that allows for enhanced airflow, so you sleep dry. The invisible aterproof barrier reduces the buildup of allergens in your bed and resists liquids and stains for clean sleep. Machine-washable and dryer safe for easy care.

Resonable price and good fit.. Dave. Fri, 03 May 2024

A mattress protector protects you against dust, perspiration, fluid, urine, and allergen. We know that our mattress costs us thousands of dollars. With just one accidental spill, our expensive mattress can be left with permanent odor and un-washable stains. Using a mattress protector is recommended for those with young kids and pets. It also helps those suffering from asthma, allergies, and incontinence. Our mattress protector is designed not to cause any interference with your current level of mattress firmness. Whatever you currently feel on your bed, you will not notice any difference once the protector is being used. Lightweight and portable, this mattress protector also allows you to bring it with you during travel or sleepover. You will have peace of mind knowing that you are protected anywhere you go.

Exactly what I needed! Basic fitted protector, so far it's done it job!. Elizabeth. Calabasas, CA. Thu, 04 Dec 2025

Keep your mattress looking and feeling like-new with gold-standard, 100% waterproof protection and a soft-knit layer designed to maximize the comfort of your Purple mattress. Perfect for mattresses 8” - 15.5” in height.

Great addition to mattress. Sandra Lee Stevens. CA. Thu, 08 Oct 2026

From the #1 best-selling allergy bedding brand, AllerEase Cotton Fresh Zippered Mattress Protector delivers the quality, healthy night's sleep that we all deserve. Made from 100% cotton, waterproof top fabric provides both softness and protection from spills and stains. The HeiQ Fresh finish inhibits the growth of odor-causing bacteria while the allergen barrier blocks unhealthy household allergens like dust mites, pollen, and pet dander from collecting in your mattress. Backed by the AllerEase Lifetime warranty, this zippered protector is bedbug bite-proof and machine washable for easy care.  

Very soft I love that it protect my mattress all around !. Anonymous. Sun, 23 Aug 2026

Our mattress protectors are lined with a silent TPU waterproof membrane, which can perfectly protect your mattress from perspiration, accidental spills, and bodily fluids like sweat or urine.

Advanced fabric uniquely constructed for powerful mattress protection without sacrificing breathability and comfort. After the mattress cover is sewn, attach extra interior bindings to cover seams and eliminate stitch holes. This process seals the cover to help prevent bed bugs and dust mites from entering or escaping. Encasements are designed with an exclusive triple-seal closure system including an inner flap, a hook and loop corner seal, and a nylon zipper for additional security coverage. In addition to premium waterproof and stain-resistant protection, each mattress protector boasts soft and breathable knit fabric.

Waonderful. Just what I wanted.. Loretta. US. Sat, 01 Jun 2024

This waterproof mattress cover keeps your mattress comfortable without compromising on protection. The DRYSEAL™ waterproof barrier guarantees 100% reliable water protection from liquids and spills. A fully elasticized skirt completes the design and fits snugly around mattresses. For hassle-free maintenance, machine wash and tumble dry this white mattress cover.

Achieve the deep, restful sleep you've been looking for with the twin mattress cover by Lavish Home. Made from super soft rayon from bamboo fibers, the cover is breathable and hypo-allergenic, protecting from allergens and dust mites while helping to extend the life of your mattress. The bed protector features a full skirt with deep pockets and elastic edges for no-slip corners that will fit regular or high-profile twin mattresses.

Nice quality. Fits nice . Pretty thick. Mary. US. Fri, 11 Sep 2026

The best mattress protector combines moisture protection, antimicrobial odor protection, and a cool-to-the-touch silky soft feeling! The silky smooth top layer of cool touch performance fabric blend of polyester and nylon. Treated with an additional layer of dew Salvador antimicrobial protection for up to 30 home laundering. Deep pocket sure-grip side panels that are deep pocket up to 18". Oeko-Tex-certified textiles are certified free of harmful chemicals. Clean sleep antimicrobial cool to the touch durable for repeat washings water block waterproof protection odor reduction sure-grip side panels - deep pocket up to 18" Oeko-tex certified textiles are certified free of harmful chemicals easy care - machine wash & dry hypoallergenic - reduces the reaction to household allergen stop fabric.

It fit well! No smell! Very happy with it. Shernella. US. Sat, 29 Aug 2026

Keep your mattress looking and feeling like-new with gold-standard, 100% waterproof protection and a soft-knit layer designed to maximize the comfort of your Purple mattress. Extended deep pocket sizing makes a perfect fit with mattresses 15.5” - 20” in height.

Its very functional if you have young kids or babies sleeping in your bed.. Anonymous. Friendswood Tx. Wed, 07 Oct 2026

Our premium mattress protector was created to protect the life of your mattress while also ensuring that you still have a soft, comfortable, and quiet night's sleep. This mattress protector has a 100% waterproof membrane backing that will repel all liquids to keep your mattress safe from stains.

Great quality.. Dana. Milwaukee, WI. Wed, 07 Oct 2026

The All-in-One Mattress Protector with Bed Bug Blocker® is the leading encasement solution for complete mattress protection. Crafted from technologically advanced, water and stain-resistant fabrics, this protector offers a soft, breathable, and quiet sleep surface. Engineered to deliver superior protection against allergens, bed bugs, dust mites, accidental spills, and incontinence—making it the ideal choice for families and individuals with allergies, asthma, or other respiratory conditions. The generous stretch sidewalls allow for a smooth and neat contour fit on all mattresses and box springs, up to 15 inches deep. Choose the All-in-One Mattress Protector to create a healthier sleeping environment for you and your family.

Not wanting to takes any chances getting those little critters. He live with 2 other guys in a group home setting. So you do all you can to keep him safe.. Patricia. Saint. Paul, IN. Tue, 27 Oct 2026

Cotton bed bug and dust mite mattress protector helps eliminate bed bugs, and dust mites is waterproof and hypoallergenic. This six-sided bed bug protector encases the entire mattress and will eliminate the passage of bed bugs in or out of your mattress. Serves as a means for treatment and prevention. Breathable 100% cotton fabric padded and quilted for better comfort, chemical-free material, bed bug proof zipper perfect and easy fit for your mattress machine washable in cold water and tumble dry on low heat it's up to 14" mattress twin: 38" x 75" x 14" this bed bug protector encases the pillow and will eliminate passage of bed bugs in or out of your mattress. Serves as a means for treatment and prevention.

Extend the life of your mattress and safeguard your health with the Simply Soft™ deluxe mattress protector. Constructed to shield against spills, allergens, mold, dust mites, odors, fluids, perspiration, and more. This superior mattress protector is invaluable for those with kids, pets, or allergies. Made with a soft terry cotton surface for a noiseless, breathable, and comfortable sleep as well as a 100% waterproof layer for safeguarding the health of your family and protection of your mattress.

It is not only a fact, but it is also a science that natural wool is the mightiest of fibers. myPad features a 0.5” loft of this mighty fiber. The Shropshire wool fibers, with their “spring-action”, provide luscious comfort, and relief from pressure points. Wool’s miraculous capabilities prevent overheating or overcooling during sleep. “Biowash” treatment of the wool insures the myPad to be chemical-free resulting in more healthy sleep. The 100% natural cotton percale cover adds to the luxurious sleep as it follows the curvature of the spine. Quickly wicks away moisture without making you feel cold or clammy. Less time is spent tossing and turning. Eco-friendly mattress pad for all four seasons. Lasts for many years with proper care. Wool out-performed other fibers used for bedding.

It’s good and as described. It is relatively thin which I think was accurately stated in the description. If that is what you are looking for I think it’s good I just think for me I would prefer something thicker.. Kris. Newport, OR. Tue, 03 Jun 2025

Designed for hot sleepers or hot climates, Bedgear Ver-tex Mattress Protectors guard against spills while keeping you comfortable with a top layer of instant-cooling fabric that reduces overheating while you sleep. This protector features a Powerband® for secure fit and grip, keeping this layer smooth and invisible beneath your sheets – Adjustable base friendly.

Mattress ver-tex protector keep my bed cool even on hot nights.. Larry. Portage, MI. Mon, 21 Aug 2023

This mattress protector provides an essential layer of protection for your sleep surface. Crafted from polyester, this piece features a waterproof design that helps guard against spills and accidents. The zippered closure wraps around your mattress for a secure fit that stays in place throughout the night. It also provides a barrier against bed bugs, dust mites, and common allergens to help promote a cleaner sleeping environment. We also love that its machine-washable construction makes it simple to refresh whenever it needs a deep clean.

Great and easy to put on the mattress, but very crinkly and noisy. Thankfully I have a mattress pad on top of it so I cant hear anything but if you only have a sheet over top of it, there may be some noise.. Samantha. Port Saint Lucie, FL. Mon, 06 Jul 2026

Your night's sleep has never been better! with the Sanitized Waterproof Mattress Protector you are set up for a superior nights sleep. Treated with sanitized antimicrobial hygiene function that effectively prevents odors and mildew strains. Also protects from dust mites, liquid and is complete as an allergen blocker. Extend the life of your mattress and sleep easily by using the mattress protector.

Feel comfortable and waterproof I like this. Debra. Sedalia, MO. Wed, 15 May 2019

Lakeshore is the most amazing fabric you will ever experience. Made via nanotechnology, Lakeshore resists water and stains while retaining 100% of the natural feel of the fabric. Lakeshore is not a coating and will not wash out, so the product is long-lasting. This mattress cover has a zipper closure and fully encases the mattress.

It works fine, but goes all the way around the mattress ~ tough to get on a large and heavy King Size Mattress!. Charlene. Antrim, NH. Thu, 07 Dec 2017

This mattress topper refreshes your sleep surface with a layer of plush comfort. It features a polyester cover that feels soft to the touch, while the cushy filling provides essential support to help you relax throughout the night. The checkerboard quilted pattern prevents the fill from shifting, ensuring an even distribution of weight across the bed. Designed for practicality, its elastic skirt stretches to accommodate a range of mattress depths for a secure fit. We also love that this topper is machine washable for effortless maintenance.

I was so glad to find these because it does not stain as easily as the white ones did. Like it so much I got rid of all of my white ones.. Beverly. US. Sat, 05 Sep 2026

Luxury Premium Hypoallergenic and Waterproof Mattress Protector, Twin, Full, Queen, King The mattress is ultra-soft, skin-friendly, 100% waterproof, and breathable. Its back coating protects the mattress against liquids and deep pockets fit up to 16 inches. Its soft, comfortable, and smooth top have no crinkling or plastic feel. Rayon Mattress with ultra-soft top and improved stitching helps it to last longer.

Our mattress protectors are completely waterproof and breathable allowing for air circulation and they effectively repel all liquids including accidental spills and bodily fluids such as sweat or urine. They were engineered to endure the endless rigor of multiple spills, soils, and washes.

great mattress cover fit perfect. Jb. Gilbert, SC. Fri, 25 Feb 2022

StainGuard® Poly Terry Mattress Protectors provide a comfortable, low cost solution to protecting the top of your mattress against stains. Made with plush cotton terry fabric, StainGuard mattress covers provide excellent surface moisture and stain protection for the sleeper. These mattress protectors offer 1-sided stain protection to ensure that the top of your mattress remains clean, and can provide some dust mite and allergen resistance. Cotton terry mattress covers are ideal for guest bedroom and minimal use mattresses.

Betty. US. Tue, 21 Apr 2026

Sleep confidently with the Fresh Ideas Fitted Vinyl Mattress Protector. Simple, dependable protection designed to keep your mattress clean. A hypoallergenic suface that is waterproof to block unexpected spills and stains, and extend the life of your mattress. Featuring 9" deep pockets and fitted elastic corners to keep your protector in place all night. Perfect for kids’ rooms, guest beds, dorms, vacation rentals, and everyday household use. Fresh Ideas delivers practical, long-lasting protection you can count on.

Product as described and arrived on time.. Lisa. Salem, IN. Thu, 29 Jan 2026

Bought for vacation rental beds. They fit great and do not feel like plastic. We'll see if they really work next September after the rental season.. Bruce. Dallastown, PA. Mon, 29 Mar 2021

Designed with your comfort in mind, this mattress protector not only protects but will also ensure a peaceful night's sleep! Suited for personal use or a guest bed, the mattress protector makes a great addition to your home. Infused with lavender, which is known to promote relaxation, reduce stress, and ease anxiety for a more restful night’s sleep. Great for those with Kids, Pets, Allergies, Asthma, Eczema, Or Incontinence.

Lavender scented mattress pad! Yes, please! We love it!!. Brittany. Walker, MN. Thu, 06 Apr 2023

100% Waterproof - whether you have pets or kids, accidents and spills happen. This 100% waterproof mattress protector has a polyurethane inner lining that blocks liquids and moisture from getting in. Liquids easily seep through to deeper layers of your mattress and are almost impossible to remove. Simply wrap your mattress in our premium cover, and zipper seal all the way around, and your mattress will remain waterproof, dry, and protected!

Great money spent on these items. Diana. Edinburgh In. Fri, 03 Jul 2026

Enjoy a hassle-free and good night's sleep with this Bed Bug & Dust Mite Control Water Resistant Polypropylene Basic Bed Protector Set. It is hypoallergenic and dust mite resistant, making it safe for use in homes where a family member may be suffering from allergies. This set is available in numerous sizes, which you can choose from. The Bed Bug & Dust Mite Control Water Resistant Polypropylene Basic Bed Protector Set is CPSIA or CPSC compliant. The set is water-resistant and can be machine-washed occasionally, to keep it fresh and clean.

Not what I was expecting but it works.. Jill. US. Sat, 24 Dec 2022

Deep pocket for a tailored fit.. Sharon. Waukegan. Wed, 17 Jun 2020

The 3-piece mattress and pillow protectors encase every side of your bed and pillows, shielding them from bed bugs, dust mites, dirt, dander, allergens, and liquids. The encasement can hold mattresses or box springs, while the two pillow covers fit any standard-sized pillows, and all the protectors have zippered closures for maximum protection. Made with cotton fabric, this set of mattress and pillow covers are soft, breathable, machine washable, and completely waterproof without using noisy plastic lining.