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 Size: 21" - 22" 

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 Wheels: 2 Wheel (Standard) 

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Suitcases
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22" 2-Wheeled Travel Duffel ss_pt1917813
Product Features
  • Extra large wheels
  • Heavy duty zipper
  • Large \"U\" shape top pocket
  • Four front pockets
More Options: Pattern »

22" 2-Wheeled Travel Duffel

by Rockland

from $24.43 $44.99
2-Day Delivery
  (92)
Arrives by Dec. 24
Sale
Amsterdam 21" Expandable Rolling Carry On ss_pt1917813
Product Features
  • Interior deluxe retractable push-button handle system
  • Inline skate wheels with corner protectors
  • Expandable (25% more packing capacity)
More Options: Color »

Amsterdam 21" Expandable Rolling Carry On

by Traveler's Choice

$37.99 $57.00

  (59)
Andante 22" Wheeled Duffel ss_pt1917813
Product Features
  • Locking zippers
  • Front zip pocket
  • Embroidered logo
  • End bumpers
More Options: Color »

Andante 22" Wheeled Duffel

by Samsonite

$49.95 $80.00
Free Shipping & 2-Day Delivery
  (7)
Arrives by Dec. 24
Eight Pocket 22" Rolling Duffel ss_pt1917813
Product Features
  • Eight convenient pockets for maximum packing versatility
  • U-shape top opening system for easy access to spacious main compartment
More Options: Color »

Eight Pocket 22" Rolling Duffel

by Olympia

$30.12 $40.00
2-Day Delivery
  (28)
Arrives by Dec. 24
Helium Quantum 21" Suitcase ss_pt1917813
Product Features
  • Lightweight
  • Fully lined with tie down straps and zippered mesh pocket for easy storage and security
  • Recessed locking trolley handle

Helium Quantum 21" Suitcase

by Delsey

$67.99 $160.00
Free Shipping & 2-Day Delivery
  (8)
Arrives by Dec. 24
22" 2-Wheeled Travel Duffel ss_pt1917813
Product Features
  • Recessed metal ball bearing in-line skate wheels
  • Hideaway retractable handle
  • Eight convenient pockets for maximum packing versatility
More Options: Color »

22" 2-Wheeled Travel Duffel

by Olympia

$30.45 $40.00

  (5)
Arrives by Dec. 24
ss_pt1917813
Product Features
  • Interior deluxe retractable push-button handle system
  • Inline skate wheels with corner protectors
  • Expandable (25% more packing capacity)

Amsterdam Expandable Rolling Carry - On in Burgundy

by Traveler's Choice

$41.95 $81.00
2-Day Delivery
  (5)
Arrives by Dec. 24
ss_pt1917813
Product Features
  • Maximum impact resistance
  • Multiple-stage self-locking retractable aluminum telescopic handle system
More Options: Color »

Freedom 21" Hardsided Carry-On

by Traveler's Choice

$56.99 $101.00
Free Shipping & 2-Day Delivery
  (18)
Arrives by Dec. 24
ss_pt1917813
Product Features
  • Roomy main compartment
  • Front zip pocket
  • Sturdy pull-up handle

22" 2-Wheeled Travel Duffel

by Preferred Nation

$31.95 $50.00

  (5)
Arrives by Dec. 24
ss_pt1917813
Product Features
  • Carry-on size wheeled duffel
  • Soft and noiseless wheels
  • Detachable and adjustable shoulder strap
More Options: Color »

22" Tamarak 2-Wheeled Carry-On Duffel

by J World

$56.32 $75.32
Free Shipping
  (2)
Arrives by Dec. 24
ss_pt1917813
Product Features
  • Rolling
  • Self-repairing zippers
  • U-top opening to roomy main compartment
  • Recessed metal ball bearing in-line skate wheels
More Options: Color »

22" 2 Wheeled Duffel

by Olympia

$28.99 $80.00

  (3)
Sale
ss_pt1917813
Product Features
  • Combines the best advantages of luggage and duffel bags
  • Front feet allows bag stands on its own
More Options: Color »

21" 2-Wheeled Hybrid Travel Duffel

by Athalon Sportgear

from $66.95 $200.00
Free Shipping
  (9)
ss_pt1917813
Product Features
  • Meets airline requirements for carry-on luggage
  • Deluxe antique brass hardware
  • Recessed roller bearing in-line skate wheels for smooth pulling or pushing on any surface
More Options: Color »

22" Leather 2-Wheeled Carry-On Duffel

by Claire Chase

$380.57 $759.00
Free Shipping
  (6)
Arrives by Dec. 24
ss_pt1917813
Product Features
  • Side compression straps
  • Front accessory pocket
  • Bottom protection/stand
  • Retractable push button handle
More Options: Color »

Rounder 21" Rolling Carry On

by CalPak

$58.95 $95.00
Free Shipping
  (3)
ss_pt1917813
Product Features
  • Carry-on size wheeled duffel
  • Soft and noiseless wheels
  • Expandable main compartment for more storage
  • Detachable and adjustable shoulder strap
More Options: Color »

22" Stadium 2-Wheeled Expandable Carry-On Duffel

by J World

$52.99 $61.00
Free Shipping
  (4)
Arrives by Dec. 24
Sale
ss_pt1917813
Product Features
  • Fabric: 600 D Polyester
  • Custom hardware
  • In line skate wheels
  • Fully lined interiors

Dots 22" Carry All Duffel

by Jenni Chan

$52.16 $160.00
Free Shipping
Arrives by Dec. 24
ss_pt1917813
Product Features
  • Lightweight and spacious to meet both travel and everyday needs
  • Interior organization includes compression straps and a zippered hanging pocket
More Options: Color »

CH-97 2.0 22" Expandable Wheeled Carry On

by Victorinox Travel Gear

$249.99 $500.00
Free Shipping
  (3)
Sale
ss_pt1917813
Product Features
  • Ideal for a short business trip or a long weekend
  • Patented 360 rotating handle locks into a natural ''palm-facing-the-body'' position to reduce arm and wrist stress
More Options: Color »

Werks Traveler 4.0 22" Expandable Rolling Carry On

by Victorinox Travel Gear

$263.99 $550.00
Free Shipping
  (4)
ss_pt1917813
Product Features
  • Recess handle
  • In-line skate wheels
  • Constructed from High-Tech nylon and 600D polyester

The Odyssey 21" Upright Carry-On Suitcase

by Preferred Nation

$77.99 $118.00
Free Shipping
ss_pt1917813
Product Features
  • 600D poly canvas
  • Interior mesh pocket
  • Exterior organizer pocket
  • Inline skate wheel system
More Options: Color »

Micro Monster Bag

by Mercury Luggage

$83.99 $114.00
Free Shipping
  (1)
ss_pt1917813
Product Features
  • Carry-on case
  • Leather zipper pullers for easy 'open and close'
  • Full clothes compartment on interior
  • Constructed of lightweight nylon

Carry-On 21.5" Laptop Briefcase

by Bond Street, LTD.

$87.95 $260.00
Free Shipping
ss_pt1917813
Product Features
  • TSA lock included
  • Ballistic nylon outer fabric resists moisture, dirt and abrasion
More Options: Color »

Baseline Domestic Carry-On 22" Expandable Suitcase

by Briggs & Riley

$469.00
Free Shipping
  (2)
ss_pt1917813
Product Features
  • Durable polyester fabric with dual guard
  • Oversized inline skate wheels
  • Self-repairing nylon coil zippers provide flawless operation for the life of the bag
More Options: Color »

Tpro Bold 22" Expandable Rollaboard

by Travelpro

$127.49 $300.00
Free Shipping
  (1)
Arrives by Dec. 24
ss_pt1917813
Product Features
  • Rollaboard
  • Oversized in-line skate wheels
  • Push button & self-locking retractable handle system
More Options: Color »

Conventional II 22" Rugged Rollaboard

by Traveler's Choice

$92.99 $219.99
Free Shipping
ss_pt1917813
Product Features
  • Meets airline requirements for carry-on luggage
  • Deluxe antique brass hardware
  • Recessed roller bearing in-line skate wheels for smooth pulling or pushing on any surface
More Options: Color »

Classic 22" Pullman Rolling Carry On

by Claire Chase

$404.04 $899.00
Free Shipping
  (2)
Arrives by Dec. 24
ss_pt1917813
Product Features
  • Ergonomic aluminum push-button handle system
  • Grooved handle tubes provide extra strength and handle stability when supporting totes
  • Top, side and bottom handles for easy lifting
More Options: Color »

Birmingham 21” Suitcase

by Traveler's Choice

from $69.99
Free Shipping
  (1)
ss_pt1917813
Product Features
  • Aluminum locking push button handle system
  • In-line skate ball bearing wheels in a protective corner housing
  • Uprights expand for 30% more packing capacity

Oxford II 21" Expandable Upright Suitcase

by London Fog

$119.99 $240.00
Free Shipping
  (1)
ss_pt1917813
Product Features
  • Suitcase
  • CH-97 2.0 collection
More Options: Color »

CH-97 2.0 22" Suitcase

by Victorinox Travel Gear

$279.99 $560.00
Free Shipping
ss_pt1917813
Product Features
  • Integrated ID tag and dura guard coating
  • Designed to fit into most domestic overheads with maximized packing capacity, including a garment sleeve for your hanging items
More Options: Color »

Platinum 7 22" Expandable Rollaboard Suiter

by Travelpro

$224.35 $700.00
Free Shipping
  (2)
ss_pt1917813
Product Features
  • Fits airline carry-on side requirements
  • Hidden clothes section
  • Large easy-open pullers plus combination lock

Office on Wheels / Laptop 21.5" Carry-On

by Bond Street, LTD.

$94.99 $220.00
Free Shipping
ss_pt1917813
Product Features
  • Integrates with pack-it system, suggestions included
  • 600D Poly ripstop, 600D Helix oxford, 1260D Helix ballistic
More Options: Color »

EC Adventure 22" Upright Suitcase

by Eagle Creek

from $250.00
Free Shipping
ss_pt1917813
Product Features
  • Lightweight internal retractable handle with hideaway zippered closure
  • Multiple compartments on the front, side, and top for additional storage

Rolling 22" 2 Wheeled Duffel

by Everest

$58.99 $65.95
Free Shipping
  (1)
ss_pt1917813
Product Features
  • Universal hanging system
  • Constructed of 1680D Ballistic nylon

Travel Rite Flight Companion II Overnight 21.5" Carry On Case

by Bond Street, LTD.

$113.99 $220.00
Free Shipping
  (1)
ss_pt1917813
Product Features
  • Suitcase
  • Lightweight side bound material
  • Self repairing nylon zippers with smooth zip movement
More Options: Color »

VJ1212Sigma 4 21" Expandable Carry-On Suitcase

by Skyway

from $61.99 $140.00
Free Shipping
ss_pt1917813
Product Features
  • Suitcase
  • Bungee cords on top hold jackets and accessories
  • Zippered side accessory pocket

The Glider 21" Wheeling Carry-On Suitcase

by Athalon Sportgear

$122.99 $280.00
Free Shipping
Sale
ss_pt1917813
Product Features
  • Moisture resistant vinyl laminated
  • Heavy-duty polycarbonate bottom frame structure for light weight and maximum reinforcements
  • Interior is fully lined with 210-denier polyester
More Options: Color »

22" 2-Wheeled Light Travel Duffel

by Netpack

from $59.95 $93.00
Free Shipping
  (2)
ss_pt1917813
Product Features
  • Made of rugged 1800D polyester
  • Recessed pull-up handle system
  • In-line wheels

Magnum 22" Expandable Suitcase

by Preferred Nation

$73.99 $102.00
Free Shipping
  (3)
ss_pt1917813
Product Features
  • Telescope handle extends to 41''
  • Blade wheels
  • Tuscan leather is slightly textured and soft to the touch
More Options: Color »

Tuscan First Class Rolling Suitcase

by Clava Leather

$329.99 $450.00
Free Shipping
  (1)
ss_pt1917813
Product Features
  • Megaliteâ„¢ Premium collection
  • Frameless design make each case ultra light
  • Japanese hinomoto spinner wheels spin 360 degrees which allows to tow case in multiple ways
More Options: Color »

Megalite™ Premium 21.5" Carry-On Suitcase

by IT Luggage

$119.99 $240.00
Free Shipping
Sale
ss_pt1917813
Product Features
  • Zip-pocket on front
  • Zip around opening to main compartment
  • Two side-zip pockets plus pouch inside
  • Elastic straps to secure clothing
More Options: Color »

Pastel Leather Collection 22" Wheeled Traveler Suitcase

by Piel Leather

$353.47 $740.00
Free Shipping
Sale
ss_pt1917813
Product Features
  • Front-zip compartment with two dividers
  • Zip-pocket on front
  • Zip around opening to main compartment
  • Elastic straps to secure clothing
More Options: Color »

22" Wheeled Carry On

by Piel Leather

$355.48 $740.00
Free Shipping
  (6)
ss_pt1917813
Product Features
  • Quality 3-combination lock included
  • Deluxe retractable push-button handle system
  • Recessed in-line skate ball-bearing wheels with corner protectors provide smooth and quiet rolling

El Dorado 21" Expandable Carry On Upright

by Traveler's Choice

$63.95 $72.57
Free Shipping
ss_pt1917813
Product Features
  • Suitcase
  • Number of wheels: 4
  • Fully lined interior
  • Custom YKK developed zipper prevents theft
More Options: Color »

Geo Polycarbonate Carry On 4 Wheel Spinner Travel Case

by Zero Halliburton

$495.00
Free Shipping
Arrives by Dec. 24
ss_pt1917813
Product Features
  • Suitcase
  • Number of wheels: 2
  • Fully lined interior
  • Textured grip carry handle
More Options: Color »

Classic Polycarbonate Carry On 2 Wheel Travel Case

by Zero Halliburton

$695.00
Free Shipping
Arrives by Dec. 24
ss_pt1917813
Product Features
  • Backed by a poly-cotton finish

Nevada 22" Wheeler Carry On

by Jack Georges

$348.00 $525.00
Free Shipping
Arrives by Dec. 24
ss_pt1917813
Product Features
  • Stylish and functional
  • Soft gripped leather handle
  • Two bulk-straps to secure the case firmly
More Options: Color »

Boarding Upright Tote

by Bellino

$167.99 $197.00
Free Shipping
ss_pt1917813
Product Features
  • Self repairing nylon coil zippers with ergonomic high-tensile strength zipper pulls to ensure a long effort free life of your zippers
More Options: Color »

Platinum Magnum 22" Expandable Suitcase

by Travelpro

$254.99 $600.00
Free Shipping
ss_pt1917813
Product Features
  • Separate mesh and lining zippered pockets to divvy up your gear and clothing
  • Corner housing wheel protection with glide easy metal ball bearings
More Options: Color »

Claremont 21" Suitcase

by Timberland

$119.99 $340.00
Free Shipping



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Featured Reviews
33" 2-Wheeled Duffel 33" 2-Wheeled Duffel
 5 stars
Nice big bag, easy to see everything, lots of pockets, hope it wears well
- Tracy in Redmond, WA

Eight Pocket 33" Rolling Duffel Eight Pocket 33" Rolling Duffel
 5 stars
great bag, lots of room, lots of pockets, I hope it stands up to lots of wear
- Tracy in Redmond, WA

19" Spinner Suitcase 19" Spinner Suitcase
 5 stars
This is the perfect size for my son when he spends weekends with his dad. Easy to roll and deep to hold lots of clothes and toys.
- Kristine in North Tonawanda, NY

Eight Pocket 26" Rolling Duffel Eight Pocket 26" Rolling Duffel
 5 stars
For the price I bought it for it was steal, awesome deal
- Aleksandr in Brooklyn, NY

Sedona Hardcase Spinner Sedona Hardcase Spinner
 5 stars
So user friendly! It holds way more than I expected an fit perfectly in the overhead storage bin.
- Jane in CA

Amsterdam 25" Two-Tone Expandable Rolling Suitcase Amsterdam 25" Two-Tone Expandable Rolling Suitcase
 5 stars
Great luggage for the price. Large capacity and rolls easily.
- Carol in Fairview, TN

AT3 32" Drop-Bottom 2-Wheeled Travel Duffel AT3 32" Drop-Bottom 2-Wheeled Travel Duffel
 5 stars
Has good MAIN zippers with big teeth - that's whats most important to us. The zipper for the expansion - not so good. No big loss as this bag has 4 straps that can tighten up to close the expansion
- John in Parlin, NJ

Sigma 4 29" Spinner Suitcase Sigma 4 29" Spinner Suitcase
 5 stars
Has good zippers - that's whats most important to us. Too many pieces of luggage have wound up in the trash because the zippers broke on an otherwise perfectly good piece of luggage.
- John in Parlin, NJ

Dots 360 Quattro 21" Spinner Upright Dots 360 Quattro 21" Spinner Upright
 4 stars
Bought the whole set for my sons girlfriend for her birthday..she loves the quality and the fresh look!
- Vicki in Sylvan Lake, AB

Dots 360 Quattro 25" Spinner Upright Dots 360 Quattro 25" Spinner Upright
 4 stars
Bought for a gift, very pleased with the quality..bought as a gift for a stylish young woman
- Vicki in Sylvan Lake, AB

Dots 360 Quattro 28" Spinner Upright Dots 360 Quattro 28" Spinner Upright
 4 stars
Bought this for my sons girlfriend, she loves it! I ordered her the whole set for her birthday! Happy with the quality
- Vicki in Sylvan Lake, AB

A.T Gear Ultimate Access 36" 2-Wheeled Drop Bottom Travel Duffel with Backpack Straps A.T Gear Ultimate Access 36" 2-Wheeled Drop Bottom Travel Duffel with Backpack Straps
 5 stars
my son is very pleased with everything about the bag, only time will tell if the bag holds up to the abuse that the travel agencies put it through
- Daniel in Williams Lake, BC

Tasmania 21" Expandable Hardsided Spinner Suitcase Tasmania 21" Expandable Hardsided Spinner Suitcase
 4 stars
Good bag for traveling. Lightweight, wheels have fluid movement, two seperate compartments, and although it has only seen about 2 weeks of travel I have the impression it'll be durable. At this
- Victoria in Seward, AK

Stars n' Stripes 28" Hardside Spinner Suitcase Stars n' Stripes 28" Hardside Spinner Suitcase
 4 stars
I just purchased my second Stars n' Stripes suitcase. It painted surface shows signs of ware rather quickly but that does not deter the ease at which you will locate your luggage as it come around the
- Michael in Chicago, Illinois

Serengeti 26" Spinner Suitcase Serengeti 26" Spinner Suitcase
 5 stars
I purchased several of Ricardo Beverly Hills' Savanah suitcases a few years back and have been so impressed with not only their beauty, but also how surprisingly sturdy, agile & tough they are. They
- Julie in Los Angeles, CA

22" Wheeled Traveler Suitcase 22" Wheeled Traveler Suitcase
 5 stars
Love it! Use this always when I travel - has extra pockets and big enough for a week away!
- Graeme in Wixom, MI

Show more reviews
Suitcases - Wheels: 2 Wheel (Standard), Size: 21" - 22"
You're currently shopping Suitcases filtered by "2 Wheel (Standard)" and "21" - 22"" that we have for sale online at Wayfair.com. If you're interested in Suitcases options other than "2 Wheel (Standard)" and "21" - 22"," you can further refine your filters in the left menu. Or if you want to buy Suitcases of a different kind, you can remove filters from the breadcrumbs at the top of the page. Whether you're looking for specific Suitcases like the Birmingham 21” Suitcase or something more general like Suitcases by Traveler's Choice, we have a zillion options, with free shipping on just about everything.
Read more
Buying Guides
Luggage Buying Guide
It's important to have the right tools for the job. So when your job is going on a tropical vacation, it's important to have the right luggage! Head over to our guide on buying luggage to learn about all the different types of luggage you can use, from carry-ons to garment bags.
While a backpack might be great for a short trip, a standard suitcase might make sense for longer stays. Read over our guide to get all the details.
Show More

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