Cooking times will vary based on your oven temperature, turkey size, and whether or not your turkey is full of stuffing. For example, a medium size, 12-pound stuffed turkey can take anywhere from 3½ to 4½ hours to cook in a 325 degrees F oven. A meat thermometer is the most accurate way to determine doneness—experts advise that a turkey is done when the temperature reaches 180 degrees F in the thigh, and 165 degrees F in the breast and stuffing.
Some roaster sets include lifters, tools to help you transfer heavy turkeys from the pan to the cutting board or serving plate. These tools are specially designed to help you lift safely and securely. After you've moved the turkey, let it stand for 15 minutes before carving, preferably beneath a sheet of aluminum foil to retain heat. This rest time will allow it to reabsorb some of its juices, resulting in a moister, more delicious turkey.